SCHEMBL20109310

SCHEMBL20109310

CC(C)N1c2ccccc2N(C(C)C)P1Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20109308 0.67 MAOA (0.37)
SCHEMBL30396025 0.66 SMN1; SMN2 (0.46) FAAHMGLL
SCHEMBL5000976 0.66 SMN1; SMN2 (0.46) FAAHMGLL
SCHEMBL28755272 0.62 FAAH (0.34) FAAHMGLL
SCHEMBL17911354 0.60 FAAH (0.33) FAAHMGLL
SCHEMBL16525749 0.60 HPGD (0.37) FAAHMGLL
SCHEMBL1106902 0.60 CYP2D6 (0.39)
SCHEMBL17911355 0.60 FAAH (0.33) FAAHMGLL
Bromide SCHEMBL28911957 0.59 HPGD (0.36) FAAHMGLL
SCHEMBL17916655 0.59 GAA (0.35) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633403-B2 N-heterocyclic phosphines THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (US) 2020-04-28 US disclosed
US-20180118770-A1 N-Heterocyclic Phosphines THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS 2018-05-03 US disclosed
US-20180118770-A1 N-Heterocyclic Phosphines THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118770-A1 N-Heterocyclic Phosphines NANP, PPIP5K2, PHPT1 FAAH 3458/4885MGLL 4519/4885TDP1 2513/4885
US-10633403-B2 N-heterocyclic phosphines NANP, PPIP5K2, PHPT1 FAAH 3458/4885MGLL 4519/4885TDP1 2513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.