Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109359 | 0.88 | KMT2A (0.47) | MAPTALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL20109336 | 0.86 | MEN1 (0.49) | MAPTALDH1A1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL20109333 | 0.86 | ALDH1A1 (0.49) | MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20109358 | 0.85 | KMT2A (0.48) | MAPTALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL10047305 | 0.80 | CTBP2 (0.51) | MAPTALDH1A1TDP1L3MBTL1NPC1 | |
| SCHEMBL20109355 | 0.80 | LMNA (0.50) | MAPTALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL7347631 | 0.80 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL5808567 | 0.79 | MAPT (0.52) | MAPTALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL3412717 | 0.77 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL27006313 | 0.76 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | MAPT 4371/4885ALDH1A1 4621/4885SMN1; SMN2 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.