Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17715716 | 0.91 | HSD11B1 (0.56) | HPGDHSD11B1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL24671755 | 0.90 | HTT (0.44) | DPP8DPP7HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19176806 | 0.89 | HPGD (0.52) | HPGDPOLBHSD11B1PKMALDH1A1 | |
| SCHEMBL12509435 | 0.88 | HPGD (0.54) | HPGDPOLBHSD11B1PKMALDH1A1 | |
| SCHEMBL17816044 | 0.86 | CHRNB2 (0.50) | HPGDPOLBHSD11B1PKMCHRNB2 | |
| SCHEMBL25489003 | 0.85 | HRH3 (0.54) | DPP8DPP7HSD11B1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20232739 | 0.84 | HSD11B1 (0.47) | HPGDHSD11B1ALDH1A1CHRNB2CHRNA3 | |
| SCHEMBL16015437 | 0.82 | CHRNB2 (0.46) | POLBDPP8DPP7ALDH1A1CHRNB2 | |
| SCHEMBL15515214 | 0.82 | CHRNB2 (0.48) | HPGDPOLBHSD11B1PKMALDH1A1 | |
| SCHEMBL15515212 | 0.82 | CHRNB2 (0.48) | HPGDPOLBHSD11B1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |