SCHEMBL20109430

SCHEMBL20109430

CN(c1ccccc1)c1ccc(/C=C/C=C/c2ccc(N(C)c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
LMNA P02545 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
MAPK1 P28482 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
S1PR4 O95977 1/20 0.44
HSP90AA1 P07900 1/20 0.44
S1PR1 P21453 1/20 0.44
CCR6 P51684 1/20 0.44
TLR9 Q9NR96 1/20 0.44
APP P05067 3/20 0.41
RELA Q04206 2/20 0.40
KDR P35968 1/20 0.38
CYP1A2 P05177 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NQO2 P16083 1/20 0.37
RAD52 P43351 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13236714 0.96 RELA (0.45) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL13236723 0.89 APP (0.44) MEN1KMT2ALMNAALDH1A1HPGD
SCHEMBL20109433 0.81 APP (0.45) MEN1KMT2ALMNAALDH1A1HPGD
SCHEMBL13304647 0.80 MAOB (0.47) LMNAALDH1A1MAPK1APPRELA
SCHEMBL13236725 0.80 APP (0.50) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL15678725 0.79 RELA (0.61) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL18157308 0.78 APP (0.41) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL14466727 0.77 APP (0.46) SMN1; SMN2MEN1KMT2ALMNAALDH1A1
SCHEMBL18157309 0.76 APP (0.37) MEN1KMT2ALMNAALDH1A1HPGD
SCHEMBL14465620 0.76 APP (0.37) ALDH1A1APPCYP1A2MAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10012916-B2 Photoreceptor for electrophotography, and photoreceptor cartridge and image forming apparatus employing the same S-PRINTING SOLUTION CO., LTD. (KR) 2018-07-03 US disclosed
US-20180120716-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, AND PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS EMPLOYING THE SAME S-PRINTING SOLUTION CO., LTD. (KR) 2018-05-03 US disclosed