SCHEMBL20109431

SCHEMBL20109431

Cc1ccc(N(C=C(c2ccccc2)c2ccccc2)c2ccc(/C=C/C=C/c3ccc(N(C=C(c4ccccc4)c4ccccc4)c4ccc(C)cc4)c4ccccc34)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
GAA P10253 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
APP P05067 2/20 0.32
MAPK1 P28482 1/20 0.32
PTGS2 P35354 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
CYP1B1 Q16678 1/20 0.31
FGF23 Q9GZV9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18157319 0.97 APP (0.36) TRPM8ALDH1A1CYP3A4MAPTHPGD
SCHEMBL12549940 0.97 ALDH1A1 (0.35) TRPM8ALDH1A1CYP3A4MAPTHPGD
SCHEMBL13990770 0.97 ALDH1A1 (0.35) TRPM8ALDH1A1CYP3A4MAPTHPGD
SCHEMBL18157323 0.96 APP (0.38) TRPM8ALDH1A1CYP3A4MAPTHPGD
SCHEMBL18157327 0.94 ALDH1A1 (0.35) TRPM8ALDH1A1CYP3A4MAPTHPGD
SCHEMBL13990769 0.94 MAOB (0.34) TRPM8ALDH1A1CYP3A4MAPTHPGD
SCHEMBL20109432 0.93 APP (0.34) APP
SCHEMBL9972131 0.92 MAOB (0.35) TRPM8APPKDM4E
SCHEMBL18157307 0.91 APP (0.33) TRPM8ALDH1A1CYP3A4MAPTHPGD
SCHEMBL18157322 0.91 TRPM8 (0.32) TRPM8ALDH1A1CYP3A4MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10012916-B2 Photoreceptor for electrophotography, and photoreceptor cartridge and image forming apparatus employing the same S-PRINTING SOLUTION CO., LTD. (KR) 2018-07-03 US disclosed
US-10012916-B2 Photoreceptor for electrophotography, and photoreceptor cartridge and image forming apparatus employing the same S-PRINTING SOLUTION CO., LTD. (KR) 2018-07-03 US disclosed
US-20180120716-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, AND PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS EMPLOYING THE SAME S-PRINTING SOLUTION CO., LTD. (KR) 2018-05-03 US disclosed
US-20180120716-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, AND PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS EMPLOYING THE SAME S-PRINTING SOLUTION CO., LTD. (KR) 2018-05-03 US disclosed