Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109432 | 0.96 | APP (0.34) | MAOBAPP | |
| SCHEMBL14003806 | 0.94 | KMT2A (0.32) | MAOBAPPLMNA | |
| SCHEMBL14003809 | 0.93 | KMT2A (0.32) | MAOBLMNA | |
| SCHEMBL13990770 | 0.93 | ALDH1A1 (0.35) | MAOBAPPLMNAKDM4ETRPM8 | |
| SCHEMBL12549940 | 0.93 | ALDH1A1 (0.35) | MAOBAPPLMNAKDM4ETRPM8 | |
| SCHEMBL14081233 | 0.92 | APP (0.39) | APPRELALMNAKDM4ESNCA | |
| SCHEMBL14081210 | 0.92 | MAOB (0.39) | MAOBLMNAKDM4EHDAC3HDAC4 | |
| SCHEMBL9972134 | 0.92 | MAOB (0.31) | MAOB | |
| SCHEMBL14028867 | 0.92 | MAOB (0.31) | MAOB | |
| SCHEMBL20109431 | 0.92 | TRPM8 (0.36) | APPKDM4ETRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120156599-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |
| US-7416824-B2 | Organic photoconductive material electrophotographic photoreceptor and image forming apparatus using the same | SHARP KABUSHIKI KAISHA (JP) | 2008-08-26 | — | — | US | disclosed |
| US-7416824-B2 | Organic photoconductive material electrophotographic photoreceptor and image forming apparatus using the same | SHARP KABUSHIKI KAISHA (JP) | 2008-08-26 | — | — | US | disclosed |