Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581528 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL9781616 | 0.87 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL31613217 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL12571786 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL1751717 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL28679374 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL12571807 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL12571814 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL30846143 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTHPGDHDAC1 | |
| SCHEMBL22019171 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031532-B | Thiourea-modified pyrene derivative fluorescent probe and preparation method and application thereof | 东北农业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-114031532-A | Thiourea-modified pyrene derivative fluorescent probe and preparation method and application thereof | 东北农业大学 | 2022-02-11 | — | — | CN | claimed |
| US-7964721-B2 | A mercury preferential fluorescence detectors used for detecting mercury ions; microfulidic chemical analysis | CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2011-06-21 | — | — | US | claimed |
| US-20080255346-A1 | Ratiometric fluorescent chemosensor for selective detection of Hg (II) ions | CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2008-10-16 | — | — | US | claimed |
| CN-114031532-B | Thiourea-modified pyrene derivative fluorescent probe and preparation method and application thereof | 东北农业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114031532-A | Thiourea-modified pyrene derivative fluorescent probe and preparation method and application thereof | 东北农业大学 | 2022-02-11 | — | — | CN | disclosed |
| US-7964721-B2 | A mercury preferential fluorescence detectors used for detecting mercury ions; microfulidic chemical analysis | CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2011-06-21 | — | — | US | disclosed |
| US-20080255346-A1 | Ratiometric fluorescent chemosensor for selective detection of Hg (II) ions | CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255346-A1 | Ratiometric fluorescent chemosensor for selective detection of Hg (II) ions | TRPA1, TRPM2, GRIA1 | ALDH1A1 2063/4885KDM4E 4206/4885MAPT 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.