Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosulfuric Acid SCHEMBL28604408 | 0.91 | ELANE (0.38) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| Thiosulfuric Acid SCHEMBL28604410 | 0.90 | ELANE (0.37) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL12673777 | 0.86 | ELANE (0.38) | ELANEMAPTLMNAALDH1A1VDR | |
| SCHEMBL18114101 | 0.85 | ELANE (0.44) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL18114060 | 0.85 | ELANE (0.41) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL18121451 | 0.84 | ELANE (0.40) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL18114100 | 0.84 | ELANE (0.40) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL25654130 | 0.83 | ELANE (0.40) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL18114064 | 0.83 | ELANE (0.40) | ELANEMAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL18114065 | 0.81 | ELANE (0.38) | ELANEMAPTLMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | CBS, TST, STS | ELANE 559/4885MAPT 4618/4885LMNA 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.