Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13223496 | 0.80 | DPP4 (0.43) | DPP4IDO1MEN1KMT2AEED | |
| SCHEMBL2603238 | 0.78 | DPP4 (0.44) | DPP4IDO1MEN1KMT2AHRH3 | |
| SCHEMBL18702092 | 0.77 | DPP4 (0.43) | DPP4IDO1MEN1KMT2AHRH3 | |
| SCHEMBL18701928 | 0.76 | DPP4 (0.40) | DPP4IDO1MEN1KMT2ADRD2 | |
| SCHEMBL23691777 | 0.75 | DPP4 (0.42) | DPP4IDO1MEN1KMT2AHRH3 | |
| SCHEMBL14217175 | 0.75 | DPP4 (0.42) | DPP4IDO1MEN1KMT2AHRH3 | |
| SCHEMBL13223498 | 0.74 | ALDH1A1 (0.41) | DPP4MEN1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL20110901 | 0.74 | IDO1 (0.40) | DPP4IDO1MEN1KMT2AEED | |
| SCHEMBL14176597 | 0.72 | MAPT (0.41) | DPP4IDO1MEN1KMT2AMMP13 | |
| SCHEMBL18702215 | 0.72 | SPR (0.40) | DPP4IDO1MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233190-B2 | IDO inhibitors | NEWLINK GENETICS CORPORATION (US) | 2019-03-19 | — | — | US | disclosed |
| US-20180118753-A1 | IDO Inhibitors | NEWLINK GENETICS CORPORATION | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118753-A1 | IDO Inhibitors | IDO1, IDO2, INMT | DPP4 350/4885IDO1 1/4885MEN1 2944/4885 |
| US-10233190-B2 | IDO inhibitors | IDO1, IDO2, INMT | DPP4 350/4885IDO1 1/4885MEN1 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.