SCHEMBL20111065

SCHEMBL20111065

CCCCc1ccc(C(F)(F)Oc2cc(F)c(C)c(F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.36
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 2/20 0.35
HTR2A P28223 1/20 0.35
FAAH O00519 1/20 0.35
PSEN1 P49768 1/20 0.34
CA2 P00918 2/20 0.34
CA1 P00915 1/20 0.34
RARB P10826 2/20 0.34
PLK1 P53350 2/20 0.34
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111063 0.96 HTR2A (0.41) HTR2AFAAHRARBPLK1RARA
SCHEMBL20111066 0.92 TAAR1 (0.34) PLK1L3MBTL1ALDH1A1
SCHEMBL7730335 0.90 S1PR1 (0.36) SKP2S1PR1S1PR3HTR2AFAAH
SCHEMBL7733197 0.88 S1PR1 (0.37) S1PR1S1PR3HTR2AFAAHPSEN1
SCHEMBL7729444 0.88 PSEN1 (0.36) S1PR1S1PR3HTR2AFAAHPSEN1
SCHEMBL16257990 0.86 RARB (0.40) S1PR1S1PR3RARBRARARARG
SCHEMBL7731930 0.86 S1PR1 (0.34) S1PR1S1PR3HTR2AFAAHPSEN1
SCHEMBL7731160 0.86 HTR2A (0.41) HTR2AFAAHRARBPLK1RARA
SCHEMBL20111064 0.85 KIF11 (0.33) SMN1; SMN2
SCHEMBL7730657 0.85 PSEN1 (0.37) S1PR1S1PR3HTR2AFAAHPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119011-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-05-03 US disclosed