SCHEMBL20111064

SCHEMBL20111064

CCc1ccc(C(F)(F)Oc2cc(F)c(C)c(F)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.33
LMNA P02545 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
PDE2A O00408 1/20 0.31
TSHR P16473 1/20 0.31
GAA P10253 1/20 0.31
KCNQ3 O43525 1/20 0.31
KCNQ2 O43526 1/20 0.31
KCNQ4 P56696 1/20 0.31
KCNQ5 Q9NR82 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
EPHX2 P34913 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
GRIN2B Q13224 1/20 0.30
CETP P11597 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7735331 0.89 KIF11 (0.33) KIF11LMNATAAR1PDE2ATSHR
SCHEMBL13808369 0.89 IDH1 (0.32) TAAR1
SCHEMBL20111066 0.88 TAAR1 (0.34) LMNATAAR1GAANPC1RAB9A
SCHEMBL7729284 0.86 KIF11 (0.32) KIF11LMNATAAR1PDE2ATSHR
SCHEMBL7729688 0.86 TSHR (0.36) KIF11LMNAPDE2ATSHRSMN1; SMN2
SCHEMBL20111065 0.85 SKP2 (0.36) SMN1; SMN2
SCHEMBL7731008 0.85 TSHR (0.35) PDE2ATSHREPHX2NR1H4GRIN2B
SCHEMBL16258067 0.85 MAOB (0.34) KIF11LMNATAAR1PDE2ATSHR
SCHEMBL20111063 0.84 HTR2A (0.41) LMNA
SCHEMBL7730683 0.84 TSHR (0.35) KIF11PDE2ATSHREPHX2NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119011-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-05-03 US disclosed