SCHEMBL20111240

SCHEMBL20111240

Cc1ccc2c(c1F)-c1c-2cc(OCC2CCC(C)CC2)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 4/20 0.35
PDE10A Q9Y233 1/20 0.35
HPGD P15428 3/20 0.34
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
RIPK1 Q13546 1/20 0.32
BRD4 O60885 5/20 0.32
FFAR1 O14842 1/20 0.32
PPARD Q03181 1/20 0.32
KDM2B Q8NHM5 1/20 0.31
PHF8 Q9UPP1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111285 0.86 HPGD (0.36) SCN9AHPGDHTR2AHTR2CHTR2B
SCHEMBL20111270 0.86 HPGD (0.36) SCN9AHPGDHTR2AHTR2CHTR2B
SCHEMBL20117747 0.86 HPGD (0.36) SCN9AHPGDHTR2AHTR2CHTR2B
SCHEMBL20111333 0.86 PDE10A (0.33) PDE10AHTR2AHTR2CHTR2BBRD4
SCHEMBL20117601 0.85 SCN9A (0.36) SCN9APDE10AHPGDHTR2AHTR2C
SCHEMBL20117669 0.85 SCN9A (0.43) SCN9AHPGDHTR2AHTR2CHTR2B
SCHEMBL20111361 0.85 HPGD (0.36) SCN9APDE10AHPGDHTR2AHTR2C
SCHEMBL20111449 0.82 HPGD (0.37) SCN9AHPGDHTR2AHTR2CHTR2B
SCHEMBL20117803 0.82 SCN9A (0.35) SCN9APDE10AHPGDHTR2AHTR2C
SCHEMBL20117676 0.82 HPGD (0.34) SCN9AHPGDHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed
EP-3315583-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S SCN9A 2846/4885PDE10A 1161/4885HPGD 4744/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S SCN9A 2846/4885PDE10A 1161/4885HPGD 4744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.