SCHEMBL20111287

SCHEMBL20111287

CCCc1ccc2c(c1F)-c1c-2cc(-c2cccc(F)c2)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
ELANE P08246 2/20 0.34
CTSG P08311 1/20 0.34
TAAR1 Q96RJ0 3/20 0.33
GCGR P47871 1/20 0.33
MGLL Q99685 1/20 0.32
DCK P27707 1/20 0.31
ESR2 Q92731 1/20 0.31
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
TLR8 Q9NR97 1/20 0.31
PTGER2 P43116 4/20 0.31
IDO1 P14902 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.30
MAP4K4 O95819 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111451 0.87 CTSL (0.41) CTSLCTSSCTSKELANECTSG
SCHEMBL20111204 0.80 CTSL (0.42) CTSLCTSSCTSKELANECTSG
SCHEMBL20102439 0.78 TYR (0.35) CTSLCTSSCTSKELANECTSG
SCHEMBL20111325 0.77 CTSL (0.39) CTSLCTSSCTSK
SCHEMBL20102435 0.76 RARB (0.45)
SCHEMBL8431475 0.76 MAOA (0.36) CTSLCTSSCTSK
SCHEMBL20102403 0.75 CTSL (0.36) CTSLCTSSCTSKELANECTSG
SCHEMBL20102440 0.75 CTSL (0.40) CTSLCTSSCTSKELANECTSG
SCHEMBL20117679 0.74 CTSL (0.32) CTSLCTSSCTSK
SCHEMBL20111275 0.74 HMGCR (0.41) CTSLCTSSCTSKELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-06-18 US disclosed
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119009-A1 LIQUID CRYSTAL COMPOUND HAVING BIPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE YBX1, PIEZO1, C1S CTSL 2729/4885CTSS 2436/4885CTSK 2311/4885
US-10323187-B2 Liquid crystal compound having biphenylene, liquid crystal composition and liquid crystal display device YBX1, PIEZO1, C1S CTSL 2729/4885CTSS 2436/4885CTSK 2311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.