Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23177961 | 0.83 | ATM (0.40) | MEN1POLBMAPTKMT2ACYP1A2 | |
| SCHEMBL23153239 | 0.82 | — | — | |
| SCHEMBL21706267 | 0.81 | — | — | |
| SCHEMBL22652602 | 0.78 | — | — | |
| SCHEMBL26316899 | 0.77 | GNAO1 (0.38) | — | |
| SCHEMBL25136569 | 0.77 | — | — | |
| SCHEMBL22166434 | 0.76 | — | — | |
| SCHEMBL2601347 | 0.75 | — | — | |
| SCHEMBL2614325 | 0.75 | — | — | |
| SCHEMBL18327050 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078360-A1 | MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY | E-THERAPEUTICS PLC (GB) | 2018-05-03 | — | — | WO | disclosed |