Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 7/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23177961 | 0.93 | ATM (0.40) | GNAO1ATML3MBTL1BCHEGNAI3 | |
| SCHEMBL22024003 | 0.90 | GNAO1 (0.41) | GNAO1BCHEGNAI3GNAI1 | |
| SCHEMBL22023799 | 0.88 | GNAO1 (0.39) | GNAO1GNAI3GNAI1 | |
| SCHEMBL20469164 | 0.86 | ATM (0.41) | ATML3MBTL1 | |
| SCHEMBL22024165 | 0.83 | GUSB (0.36) | GNAO1GNAI3GNAI1 | |
| SCHEMBL22024359 | 0.81 | GUSB (0.33) | GNAO1GNAI3GNAI1 | |
| SCHEMBL18879325 | 0.80 | GNAO1 (0.47) | GNAO1GNAI3GNAI1 | |
| SCHEMBL1128180 | 0.77 | CYP1A2 (0.45) | — | |
| SCHEMBL20111699 | 0.77 | MEN1 (0.31) | — | |
| SCHEMBL21191589 | 0.77 | GNAO1 (0.41) | GNAO1BCHEGNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295113-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295113-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, NOD1 | GNAO1 1661/4885ATM 2636/4885L3MBTL1 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.