Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19775882 | 0.86 | — | — | |
| SCHEMBL27324564 | 0.82 | ADRB2 (0.44) | — | |
| SCHEMBL22906802 | 0.79 | — | — | |
| SCHEMBL23298817 | 0.74 | ADH1B (0.41) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL19508535 | 0.73 | — | — | |
| SCHEMBL24440129 | 0.73 | MEN1 (0.40) | ALOX5 | |
| SCHEMBL8763196 | 0.70 | ADH1B (0.76) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL20111748 | 0.69 | ADH1B (0.44) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL31566 | 0.69 | ADH1B (0.61) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL1691160 | 0.66 | ADH1B (0.76) | ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2020219650-A1 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| WO-2018081530-A1 | COMPOSITIONS AND METHODS FOR TREATING EZH2-MEDIATED CANCER | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-05-03 | — | — | WO | disclosed |