Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | VHL | P40337 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327170 | 0.74 | ADH1B (0.43) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL8763196 | 0.73 | ADH1B (0.76) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL20111720 | 0.73 | VHL (0.64) | ADH1BADH1CADH1AADH7VHL | |
| SCHEMBL31566 | 0.72 | ADH1B (0.61) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL23298817 | 0.69 | ADH1B (0.41) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL20111749 | 0.69 | ADH1B (0.41) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL1691160 | 0.69 | ADH1B (0.76) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL5451697 | 0.69 | ADH1B (0.76) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL4633463 | 0.68 | ADH1B (0.61) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL8763263 | 0.67 | ADH1B (0.67) | ADH1BADH1CADH1AADH7ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081530-A1 | COMPOSITIONS AND METHODS FOR TREATING EZH2-MEDIATED CANCER | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-05-03 | — | — | WO | disclosed |