SCHEMBL2011192

SCHEMBL2011192

CCCCC(CC)CN1C(=O)c2cscc2C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
THRB P10828 1/20 0.44
HPGD P15428 1/20 0.44
TDP1 Q9NUW8 2/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
CHRM1 P11229 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KCNH2 Q12809 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP3A4 P08684 5/20 0.34
TSHR P16473 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15976242 0.90 ALDH1A1 (0.41) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL14881200 0.88 LMNA (0.35) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL16307253 0.88 LMNA (0.35) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL12502653 0.84 ALDH1A1 (0.46) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL9491373 0.83 ALDH1A1 (0.45) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL29783582 0.83 ALDH1A1 (0.45) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL1782530 0.81 ALDH1A1 (0.41) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL31240756 0.80 ALDH1A1 (0.44) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL28464713 0.79 KMT2A (0.42) ALDH1A1KMT2AKDM4ETHRBHPGD
SCHEMBL1498233 0.79 KMT2A (0.39) ALDH1A1KMT2AKDM4ETHRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444723-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS ENI S.p.A. (IT) 2024-10-16 EP claimed
WO-2023105475-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS ENI S.P.A. (IT) 2023-06-15 WO claimed
EP-2768880-B1 PREPARATION OF HIGH MOLECULAR WEIGHT POLYMERS BY DIRECT ARYLATION AND HETEROARYLATION UNIV LAVAL (CA) 2025-11-26 EP disclosed
CN-116478179-A Thienopyrrolidone derivative as well as preparation method and application thereof 平湖市浙江工业大学新材料研究院 2023-07-25 CN disclosed
US-10584203-B2 Preparation of high molecular weight polymers by direct arylation and heteroarylation UNIVERSITE LAVAL (CA) 2020-03-10 US disclosed
US-20170044309-A1 PREPARATION OF HIGH MOLECULAR WEIGHT POLYMERS BY DIRECT ARYLATION AND HETEROARYLATION UNIVERSITE LAVAL (CA) 2017-02-16 US disclosed
US-9505876-B2 Preparation of high molecular weight polymers by direct arylation and heteroarylation UNIVERSITE LAVAL (CA) 2016-11-29 US disclosed
US-9376529-B2 Fluoro monomers, oligomers, and polymers for inks and organic electronic devices SOLVAY USA INC. (US) 2016-06-28 US disclosed
US-20140371409-A1 PREPARATION OF HIGH MOLECULAR WEIGHT POLYMERS BY DIRECT ARYLATION AND HETEROARYLATION UNIVERSITE LAVAL (CA) 2014-12-18 US disclosed
US-8816035-B2 Photoactive polymers UNIVERSITE LAVAL (CA) 2014-08-26 US disclosed
EP-2652004-A2 FLUORO MONOMERS, OLIGOMERS, AND POLYMERS FOR INKS AND ORGANIC ELECTRONIC DEVICES Plextronics, Inc. (US) 2013-10-23 EP disclosed
US-20130048075-A1 NOVEL PHOTOACTIVE POLYMERS UNIVERSITE LAVAL (CA) 2013-02-28 US disclosed
EP-2507287-A1 NOVEL PHOTOACTIVE POLYMERS Université Laval (CA) 2012-10-10 EP disclosed
US-20120152357-A1 FLUORO MONOMERS, OLIGOMERS, AND POLYMERS FOR INKS AND ORGANIC ELECTRONIC DEVICES PLEXTRONICS, INC. 2012-06-21 US disclosed
WO-2012082893-A2 FLUORO MONOMERS, OLIGOMERS, AND POLYMERS FOR INKS AND ORGANIC ELECTRONIC DEVICES PLEXTRONICS, INC. (US) 2012-06-21 WO disclosed
WO-2011063534-A1 NOVEL PHOTOACTIVE POLYMERS UNIVERSITé LAVAL (CA) 2011-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120152357-A1 FLUORO MONOMERS, OLIGOMERS, AND POLYMERS FOR INKS AND ORGANIC ELECTRONIC DEVICES ILK, VCL, NECTIN4 ALDH1A1 579/4885KMT2A 968/4885KDM4E 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.