Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111633 | 0.77 | PIK3CA (0.32) | — | |
| SCHEMBL25040749 | 0.65 | SMN1; SMN2 (0.35) | SMYD3 | |
| SCHEMBL8320328 | 0.65 | SMN1; SMN2 (0.35) | SMYD3 | |
| SCHEMBL25041101 | 0.65 | SMN1; SMN2 (0.35) | SMYD3 | |
| SCHEMBL25038513 | 0.64 | APLNR (0.39) | SMYD3 | |
| SCHEMBL25873244 | 0.64 | LMNA (0.40) | SMYD3 | |
| SCHEMBL13621107 | 0.64 | APLNR (0.39) | SMYD3 | |
| SCHEMBL24027196 | 0.64 | SMN1; SMN2 (0.34) | SMYD3 | |
| SCHEMBL25040313 | 0.64 | APLNR (0.39) | SMYD3 | |
| SCHEMBL19544971 | 0.63 | SMYD3 (0.33) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078360-A1 | MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY | E-THERAPEUTICS PLC (GB) | 2018-05-03 | — | — | WO | disclosed |