Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192196 | 0.93 | POLB (0.41) | POLBAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL13841320 | 0.86 | APOBEC3A (0.46) | POLBAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL8220866 | 0.83 | CA12 (0.46) | SMYD3POLBL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL18712998 | 0.83 | ABL1 (0.38) | SMYD3POLBAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL4193315 | 0.83 | SMYD3 (0.39) | SMYD3POLBAPOBEC3AAPOBEC3GMEN1 | |
| Hydrochloric Acid SCHEMBL4905850 | 0.81 | TSHR (0.47) | SMYD3POLBAPOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL24477829 | 0.80 | SMYD3 (0.38) | SMYD3 | |
| SCHEMBL20111632 | 0.77 | JAK2 (0.32) | POLBAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL4327940 | 0.75 | LMNA (0.48) | SMYD3MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL357188 | 0.75 | NCF1 (0.37) | MEN1KMT2AL3MBTL1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078360-A1 | MODULATORS OF HEDGEHOG (HH) SIGNALLING PATHWAY | E-THERAPEUTICS PLC (GB) | 2018-05-03 | — | — | WO | disclosed |