Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20112979 | 0.75 | ROCK1 (0.32) | GRIA1CACNG8 | |
| SCHEMBL21382167 | 0.71 | CYP11B1 (0.35) | LPLLIPG | |
| SCHEMBL18189549 | 0.69 | AHR (0.43) | LPLLIPGGRIA1CACNG8 | |
| SCHEMBL15288616 | 0.66 | LIPG (0.40) | LPLLIPGGRIA1CACNG8 | |
| SCHEMBL18189286 | 0.65 | CSF1R (0.37) | LPLLIPG | |
| SCHEMBL18189341 | 0.64 | LIPG (0.34) | LPLLIPGGRIA1CACNG8 | |
| SCHEMBL20111129 | 0.61 | GRIA1 (0.43) | LPLLIPGGRIA1CACNG8 | |
| SCHEMBL12296391 | 0.61 | LPL (0.40) | LPLLIPG | |
| SCHEMBL13052359 | 0.60 | GRIA1 (0.41) | GRIA1CACNG8 | |
| SCHEMBL14351274 | 0.60 | LPL (0.40) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080916-A1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |