Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113083 | 0.90 | GRM7 (0.82) | GRM7P2RX7 | |
| SCHEMBL20113021 | 0.88 | GRM7 (0.78) | GRM7P2RX7LMNAPOLBALDH1A1 | |
| SCHEMBL20113104 | 0.85 | GRM7 (0.74) | GRM7ALDH1A1 | |
| SCHEMBL20113106 | 0.85 | GRM7 (0.74) | GRM7ALDH1A1 | |
| SCHEMBL20113026 | 0.85 | GRM7 (0.74) | GRM7P2RX7 | |
| SCHEMBL20113080 | 0.85 | GRM7 (0.74) | GRM7P2RX7KDM4EMAPTALDH1A1 | |
| SCHEMBL20113180 | 0.82 | GRM7 (0.69) | GRM7P2RX7 | |
| SCHEMBL20113020 | 0.81 | GRM7 (0.68) | GRM7TDP1PKMALDH1A1 | |
| SCHEMBL20113019 | 0.81 | GRM7 (0.68) | GRM7LMNAALDH1A1 | |
| SCHEMBL20113179 | 0.81 | GRM7 (0.68) | GRM7P2RX7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079862-A1 | MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | WO | disclosed |