Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.68 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113020 | 0.90 | GRM7 (0.68) | GRM7SCN9ASCN5AALDH1A1KMT2A | |
| SCHEMBL20113106 | 0.90 | GRM7 (0.74) | GRM7SCN9ASCN5AKCNH2ALDH1A1 | |
| SCHEMBL20113104 | 0.90 | GRM7 (0.74) | GRM7SCN9ASCN5AKCNH2ALDH1A1 | |
| SCHEMBL20113080 | 0.85 | GRM7 (0.74) | GRM7SCN9ASCN5AKCNH2ALDH1A1 | |
| SCHEMBL20112963 | 0.84 | GRM7 (0.49) | GRM7SCN9ASCN5AKCNH2HSP90AA1 | |
| SCHEMBL20113084 | 0.83 | GRM7 (0.66) | GRM7SCN9ASCN5AKCNH2ALDH1A1 | |
| SCHEMBL20113103 | 0.83 | GRM7 (0.65) | GRM7HSP90AA1HSP90AB1KMT2A | |
| SCHEMBL20112955 | 0.81 | GRM7 (1.00) | GRM7ALDH1A1LMNA | |
| SCHEMBL20113021 | 0.81 | GRM7 (0.78) | GRM7ALDH1A1KMT2ALMNA | |
| SCHEMBL20112958 | 0.80 | GRM7 (0.59) | GRM7SCN9ASCN5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079862-A1 | MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | WO | disclosed |