Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.74 |
| ▸ | P2RX7 | Q99572 | 14/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20112955 | 0.85 | GRM7 (1.00) | GRM7P2RX7 | |
| SCHEMBL20113021 | 0.85 | GRM7 (0.78) | GRM7P2RX7KMT2AMEN1EPHX2 | |
| SCHEMBL20112960 | 0.82 | GRM7 (0.64) | GRM7P2RX7 | |
| SCHEMBL20113020 | 0.81 | GRM7 (0.68) | GRM7KMT2ANPC1 | |
| SCHEMBL20113104 | 0.81 | GRM7 (0.74) | GRM7KMT2AMEN1NPC1 | |
| SCHEMBL20113106 | 0.81 | GRM7 (0.74) | GRM7KMT2AMEN1NPC1 | |
| SCHEMBL20113080 | 0.81 | GRM7 (0.74) | GRM7P2RX7KMT2AMEN1RAB9A | |
| SCHEMBL20113083 | 0.80 | GRM7 (0.82) | GRM7P2RX7KMT2AMEN1EPHX2 | |
| SCHEMBL19960417 | 0.78 | GRM7 (0.66) | GRM7PDE6D | |
| SCHEMBL20113019 | 0.77 | GRM7 (0.68) | GRM7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079862-A1 | MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | WO | disclosed |