Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113106 | 0.90 | GRM7 (0.74) | GRM7ALDH1A1KMT2ASMN1; SMN2SCN5A | |
| SCHEMBL20113104 | 0.90 | GRM7 (0.74) | GRM7ALDH1A1KMT2ASMN1; SMN2SCN5A | |
| SCHEMBL20113019 | 0.90 | GRM7 (0.68) | GRM7ALDH1A1KMT2ASCN5ASCN9A | |
| SCHEMBL20113021 | 0.85 | GRM7 (0.78) | GRM7ALDH1A1KMT2AGAA | |
| SCHEMBL20113080 | 0.85 | GRM7 (0.74) | GRM7ALDH1A1KMT2ASCN5ASCN9A | |
| SCHEMBL20112964 | 0.84 | GRM7 (0.49) | GRM7ALDH1A1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL20113084 | 0.83 | GRM7 (0.66) | GRM7ALDH1A1KMT2ASMN1; SMN2SCN5A | |
| SCHEMBL20113103 | 0.83 | GRM7 (0.65) | GRM7KMT2A | |
| SCHEMBL19960417 | 0.82 | GRM7 (0.66) | GRM7GAA | |
| SCHEMBL20113026 | 0.81 | GRM7 (0.74) | GRM7KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018079862-A1 | MGLUR7 MODULATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | WO | disclosed |