Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15799090 | 0.85 | LPL (0.44) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL15333263 | 0.75 | LPL (0.44) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL5475399 | 0.73 | PRMT5 (0.47) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL20120123 | 0.71 | PDE3B (0.37) | PRMT5WDR77LPLLIPG | |
| SCHEMBL12502513 | 0.71 | JAK2 (0.46) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL30379604 | 0.71 | PRMT5 (0.42) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL1519972 | 0.71 | PRMT5 (0.42) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL15799446 | 0.70 | PRMT5 (0.41) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL17205845 | 0.69 | PRMT5 (0.39) | PRMT5WDR77LPLLIPGGSK3A | |
| SCHEMBL28391117 | 0.69 | LIPG (0.50) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080916-A1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |