Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2255158 | 0.71 | NNMT (0.44) | PDE2A | |
| SCHEMBL29935362 | 0.69 | CCR1 (0.46) | CCR1ALDH1A1 | |
| SCHEMBL6629423 | 0.68 | CCR1 (0.50) | CCR1ALDH1A1 | |
| SCHEMBL20113756 | 0.67 | CCR1 (0.41) | CCR1ALDH1A1 | |
| SCHEMBL29956915 | 0.66 | CCR1 (0.43) | CCR1ALDH1A1 | |
| SCHEMBL13723445 | 0.65 | CCR1 (0.46) | CCR1ALDH1A1 | |
| SCHEMBL21817861 | 0.65 | CCR1 (0.46) | CCR1ALDH1A1 | |
| SCHEMBL29951560 | 0.65 | CCR1 (0.46) | CCR1ALDH1A1 | |
| SCHEMBL29954702 | 0.65 | CCR1 (0.46) | CCR1ALDH1A1 | |
| SCHEMBL25851278 | 0.65 | CCR1 (0.46) | CCR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060563-B1 | RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |