Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216296 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4100287 | 0.79 | IDO1 (0.52) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL563548 | 0.78 | LMNA (0.50) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4798435 | 0.78 | NPC1 (0.53) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL19520755 | 0.78 | IDO1 (0.53) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10591756 | 0.76 | LMNA (0.49) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL15462253 | 0.76 | MAPT (0.53) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10048212 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10047710 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2730689 | 0.74 | SMN1; SMN2 (0.85) | SMN1; SMN2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009426-B1 | 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT | KAKEN PHARMA CO LTD (JP) | 2018-05-02 | — | — | EP | disclosed |