Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 11/20 | 0.50 |
| ▸ | PFKFB4 | Q16877 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796409 | 0.84 | PFKFB3 (0.66) | PFKFB3PFKFB4 | |
| SCHEMBL793742 | 0.81 | PFKFB3 (0.52) | PFKFB3PFKFB4MAPTALDH1A1 | |
| SCHEMBL793661 | 0.79 | LMNA (0.53) | PFKFB3PFKFB4MAPTALDH1A1 | |
| SCHEMBL794137 | 0.77 | PFKFB3 (0.57) | PFKFB3PFKFB4 | |
| SCHEMBL794304 | 0.77 | PFKFB3 (0.63) | PFKFB3PFKFB4MAPTALDH1A1POLB | |
| SCHEMBL27943370 | 0.77 | MMP2 (0.59) | PFKFB3PFKFB4MAPTALDH1A1 | |
| SCHEMBL793780 | 0.76 | PFKFB4 (0.57) | PFKFB3PFKFB4MAPT | |
| SCHEMBL795010 | 0.76 | PFKFB3 (0.68) | PFKFB3PFKFB4MAPT | |
| SCHEMBL793709 | 0.76 | PFKFB4 (0.70) | PFKFB3PFKFB4MAPT | |
| SCHEMBL794521 | 0.76 | PFKFB4 (0.57) | PFKFB3PFKFB4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-B1 | SULFONAMIDE COMPOUNDS | KANCERA AB (SE) | 2018-05-02 | — | — | EP | disclosed |