Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629084 | 1.00 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1POLBSLC13A5 | |
| SCHEMBL2011582 | 0.96 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1POLBSLC13A5 | |
| SCHEMBL12629080 | 0.96 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1POLBSLC13A5 | |
| SCHEMBL2011504 | 0.92 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1PKMRAB9A | |
| SCHEMBL12628159 | 0.92 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1PKMRAB9A | |
| SCHEMBL12628174 | 0.90 | KMT2A (0.58) | ALDH1A1KMT2AMEN1POLBSLC13A5 | |
| SCHEMBL2010853 | 0.90 | KMT2A (0.58) | ALDH1A1KMT2AMEN1POLBSLC13A5 | |
| SCHEMBL12628186 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1PKMRAB9A | |
| SCHEMBL2013800 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1PKMRAB9A | |
| SCHEMBL2011797 | 0.89 | KMT2A (0.56) | ALDH1A1KMT2AMEN1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |