Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12630261 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL29170692 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL2009080 | 0.83 | KDM4E (0.48) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL2009082 | 0.83 | KDM4E (0.48) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL21538827 | 0.83 | KDM4E (0.48) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL2015570 | 0.80 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL2015567 | 0.80 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL31172655 | 0.80 | PDCD1 (0.46) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL21538807 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL424747 | 0.79 | TUBB4A (0.54) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025063272-A1 | NICOTINAMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL PLANT DISEASE CONTROL AGENT | クミアイ化学工業株式会社 | 2025-03-27 | — | — | WO | disclosed |
| CN-112004811-B | Compounds that modulate AMPA receptor function | 加的夫大学学院咨询有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20230000847-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | DRAIG THERAPEUTICS LTD (GB) | 2023-01-05 | — | — | US | disclosed |
| US-11298345-B2 | Compounds that modulates AMPA receptor function | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-04-12 | — | — | US | disclosed |
| EP-3560923-B1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3560923-B1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| US-20210113539-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | DRAIG THERAPEUTICS LTD (GB) | 2021-04-22 | — | — | US | disclosed |
| CN-112004811-A | Compounds that modulate AMPA receptor function | 加的夫大学学院咨询有限公司 | 2020-11-27 | — | — | CN | disclosed |
| EP-3560923-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-10-30 | — | — | EP | disclosed |
| EP-3560923-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-10-30 | — | — | EP | disclosed |
| US-20140315794-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL LIMITED (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140315794-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL LIMITED (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140315794-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL LIMITED (US) | 2014-10-23 | — | — | US | disclosed |
| US-8618126-B2 | Antiparisitic dihydroazole compounds and compositions comprising same | MERIAL LIMITED (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2513104-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | Merial Limited (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075591-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL LIMITED (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011075591-A1 | ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL LIMITED (US) | 2011-06-23 | — | — | WO | disclosed |
| US-20110152312-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL, INC. | 2011-06-23 | — | — | US | disclosed |
| US-20110152312-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL, INC. | 2011-06-23 | — | — | US | disclosed |
| US-20110152312-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | MERIAL, INC. | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000847-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | GRIN1, GRM1, GRIN2A | SMN1; SMN2 2277/4885NPC1 2905/4885RAB9A 3171/4885 |
| US-20140315794-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | DDT, CYP1A1, CYP1A2 | SMN1; SMN2 2205/4885NPC1 1848/4885RAB9A 897/4885 |
| US-20110152312-A1 | ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME | DDT, CYP1A1, CYP1A2 | SMN1; SMN2 2205/4885NPC1 1848/4885RAB9A 897/4885 |
| US-20210113539-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | GRIN1, GRM1, GRIN2A | SMN1; SMN2 2277/4885NPC1 2905/4885RAB9A 3171/4885 |
| US-11298345-B2 | Compounds that modulates AMPA receptor function | GRIN1, GRM1, GRIN2A | SMN1; SMN2 2277/4885NPC1 2905/4885RAB9A 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.