Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18030924 | 0.84 | EGFR (0.51) | IMPDH2GPR3NQO2EGFRSRC | |
| SCHEMBL18030919 | 0.81 | GPR3 (0.52) | IMPDH2GPR3NQO2EGFRSRC | |
| SCHEMBL16203623 | 0.78 | KDM4E (0.59) | GPR3TOP2ANQO2MAPTKDM4E | |
| SCHEMBL18030937 | 0.77 | KDM4E (0.50) | IMPDH2GPR3EGFRSRCMAPT | |
| SCHEMBL14313953 | 0.76 | GPR3 (0.71) | GPR3TOP2ANQO2MAPTKDM4E | |
| SCHEMBL20115855 | 0.76 | KDM4E (0.68) | IMPDH2GPR3NQO2EGFRSRC | |
| SCHEMBL18030933 | 0.73 | IMPDH2 (0.46) | IMPDH2GPR3TOP2ANQO2EGFR | |
| SCHEMBL18028323 | 0.72 | BCHE (0.43) | IMPDH2GPR3EGFRSRCMAPT | |
| SCHEMBL18030940 | 0.71 | GPR3 (0.57) | IMPDH2GPR3EGFRSRCMAPT | |
| SCHEMBL18030917 | 0.71 | IMPDH2 (0.46) | IMPDH2GPR3EGFRSRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061759-B1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO (JP) | 2019-12-25 | — | — | EP | disclosed |
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |