Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146705 | 0.85 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL68894 | 0.83 | TSHR (0.60) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL10482619 | 0.83 | ALDH1A1 (0.72) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL11380576 | 0.80 | ALDH1A1 (0.68) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL4506446 | 0.80 | ALDH1A1 (0.68) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL4518634 | 0.78 | ALDH1A1 (0.65) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL3030839 | 0.77 | ALDH1A1 (0.74) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL10367142 | 0.77 | ALDH1A1 (0.63) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL18202408 | 0.76 | ALDH1A1 (0.48) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL20480462 | 0.75 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |