Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMO | Q99835 | 1/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.55 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.55 |
| ▸ | TUBB | P07437 | 3/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116123 | 0.89 | TSHR (0.57) | TSHRLMNAALOX15MAPK1ALDH1A1 | |
| SCHEMBL20116111 | 0.88 | TUBB4A (0.58) | TSHRLMNAALOX15MAPK1ALDH1A1 | |
| SCHEMBL20116646 | 0.87 | HTT (0.59) | TSHRLMNAALOX15MAPK1ALDH1A1 | |
| SCHEMBL20116645 | 0.86 | HTT (0.58) | TSHRLMNAALOX15MAPK1HTT | |
| SCHEMBL20116204 | 0.86 | HTT (0.58) | TSHRLMNAALOX15MAPK1HTT | |
| SCHEMBL20117193 | 0.85 | SMO (0.55) | TSHRLMNAALOX15MAPK1ALDH1A1 | |
| SCHEMBL20116462 | 0.85 | SMO (0.57) | TSHRLMNAALOX15MAPK1HTT | |
| SCHEMBL30720960 | 0.85 | SMO (0.57) | TSHRLMNAALOX15MAPK1HTT | |
| Hydrochloric Acid SCHEMBL20660764 | 0.85 | HTT (0.58) | TSHRLMNAALOX15MAPK1HTT | |
| Hydrochloric Acid SCHEMBL30506238 | 0.85 | HTT (0.58) | TSHRLMNAALOX15MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| EP-3700934-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | TSHR 4679/4885LMNA 1966/4885ALOX15 557/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | TSHR 4679/4885LMNA 1966/4885ALOX15 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.