SCHEMBL201162

SCHEMBL201162

CCCCCCCCCCCCc1cccc(CCCCCCCCCCCC)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.68
PTGS2 P35354 1/20 0.68
TYR P14679 2/20 0.61
LIPG Q9Y5X9 1/20 0.60
BID P55957 3/20 0.59
MCL1 Q07820 3/20 0.59
BCL2L1 Q07817 2/20 0.59
BAK1 Q16611 2/20 0.59
KAT8 Q9H7Z6 2/20 0.59
SAE1 Q9UBE0 2/20 0.59
PPARG P37231 1/20 0.59
PPARA Q07869 1/20 0.59
EP300 Q09472 1/20 0.59
KAT2A Q92830 1/20 0.59
KAT2B Q92831 1/20 0.59
KAT5 Q92993 1/20 0.59
GABRA1 P14867 1/20 0.54
GABRB2 P47870 1/20 0.54
TP53 P04637 2/20 0.53
CYP3A4 P08684 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11616767 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11784149 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4960231 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11615237 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL199708 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4962037 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL10926251 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11618297 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4959229 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11621072 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450483-B1 Conductive resin composition MITSUI TOATSU CHEMICALS (JP) 1997-06-25 EP claimed
WO-1996037535-A1 METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-11-28 WO claimed
US-5149465-A Polyphenylene Ether, Maleimide-Styrene Copolymer, Low Molecular Weight Polystyrene MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-09-22 US claimed
EP-0450483-A2 Conductive resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-10-09 EP claimed
EP-3227366-B1 WATER EXPANDABLE POLYMER BEADS CONTAINING LATEX PARTICLES SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-11 EP disclosed
US-10131769-B2 Flame-retardant polystyene composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-11-20 US disclosed
US-20180265676-A1 FLAME-RETARDANT POLYSTYENE COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-09-20 US disclosed
EP-3227378-B1 FLAME-RETARDANT POLYSTYRENE COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-09-05 EP disclosed
US-9850361-B2 Water expandable polymer beads containing latex particles SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-12-26 US disclosed
US-20170313842-A1 WATER EXPANDABLE POLYMER BEADS CONTAINING LATEX PARTICLES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-11-02 US disclosed
EP-3227378-A1 FLAME-RETARDANT POLYSTYRENE COMPOSITION SABIC Global Technologies B.V. (NL) 2017-10-11 EP disclosed
EP-3227366-A1 WATER EXPANDABLE POLYMER BEADS CONTAINING LATEX PARTICLES SABIC Global Technologies B.V. (NL) 2017-10-11 EP disclosed
US-4086253-A 3,3',5,5'-Tetra-substituted diphenoquinone from 2,6-disubstituted phenol by phase-transfer catalysis THE DOW CHEMICAL COMPANY (US) 1978-04-25 US disclosed
US-4064158-A Process for the preparation of an organomercaptophenol from sulfur, a 2,6-disubstituted phenol, and an activated olefin or an epoxy compound GENERAL ELECTRIC COMPANY (US) 1977-12-20 US disclosed
US-4054553-A MANGANESE COMPLEX CATALYST GENERAL ELECTRIC COMPANY (US) 1977-10-18 US disclosed
US-3979460-A ANTIOXIDANTS GENERAL ELECTRIC COMPANY (US) 1976-09-07 US disclosed
US-3972851-A Preparation of polyphenylene oxide using a manganese(II) ortho-hydroxyarene-oxime chelate reaction promoter GENERAL ELECTRIC COMPANY (US) 1976-08-03 US disclosed
US-3965069-A Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst GENERAL ELECTRIC COMPANY (US) 1976-06-22 US disclosed
US-3962180-A COPPER, MANGANESE OR COBALT AND AN AMINE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-06-08 US disclosed
US-3956242-A Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter GENERAL ELECTRIC COMPANY (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180265676-A1 FLAME-RETARDANT POLYSTYENE COMPOSITION PFAS, PCBP1, FGFR3 ALOX5 1974/4885PTGS2 2675/4885TYR 2123/4885
US-10131769-B2 Flame-retardant polystyene composition PFAS, PCBP1, FGFR3 ALOX5 1974/4885PTGS2 2675/4885TYR 2123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.