SCHEMBL2011658

SCHEMBL2011658

C=Cc1ccccc1C(CO)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.37
ALDH1A1 P00352 4/20 0.36
LMNA P02545 2/20 0.35
TRPA1 O75762 4/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HTR2A P28223 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
RIPK1 Q13546 1/20 0.34
AOC3 Q16853 3/20 0.32
HRH1 P35367 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28023196 0.79 AOC3 (0.40) CYP2C19ALDH1A1LMNASLC6A2SLC6A4
SCHEMBL22160163 0.79 MEN1 (0.46) CYP2C19ALDH1A1LMNAL3MBTL1MAPK1
SCHEMBL19876860 0.76 ALDH1A1 (0.41) CYP2C19ALDH1A1LMNASLC6A2SLC6A4
SCHEMBL28472908 0.76 TSHR (0.38) ALDH1A1LMNATRPA1SLC6A2
SCHEMBL11210594 0.75 LMNA (0.38) CYP2C19ALDH1A1LMNAHTR2ARIPK1
SCHEMBL28838274 0.75 ALDH1A1 (0.40) CYP2C19ALDH1A1LMNASLC6A2SLC6A4
SCHEMBL177911 0.75 ALDH1A1 (0.40) ALDH1A1LMNATRPA1HTR2AKDM4E
SCHEMBL2944385 0.73 ALDH1A1 (0.46) ALDH1A1LMNA
SCHEMBL23748278 0.73 ALDH1A1 (0.43) CYP2C19ALDH1A1LMNAMAPK1
SCHEMBL5073357 0.73 TYR (0.42) CYP2C19ALDH1A1LMNAHTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2336340-A1 Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step Marliere, Philippe (FR) 2011-06-22 EP disclosed
EP-2336341-A1 Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step Marliere, Philippe (FR) 2011-06-22 EP disclosed