SCHEMBL28023196

SCHEMBL28023196

C=Cc1ccccc1C(CCC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.40
LMNA P02545 3/20 0.37
SLC6A4 P31645 3/20 0.36
RIPK1 Q13546 1/20 0.36
FFAR1 O14842 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
HRH1 P35367 7/20 0.35
HTR2A P28223 6/20 0.35
SIGMAR1 Q99720 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CHRM2 P08172 2/20 0.33
CHRM1 P11229 2/20 0.33
ADRA1A P35348 2/20 0.33
KCNH2 Q12809 2/20 0.33
ESR1 P03372 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
MAPT P10636 1/20 0.33
KCNE1 P15382 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11406751 0.91 FFAR1 (0.42) AOC3LMNARIPK1FFAR1GPR84
SCHEMBL177911 0.80 ALDH1A1 (0.40) AOC3LMNAGPR84HRH1HTR2A
SCHEMBL17292858 0.79 CSNK1E (0.43) SIGMAR1ALDH1A1
SCHEMBL11210594 0.79 LMNA (0.38) AOC3LMNARIPK1HRH1HTR2A
SCHEMBL8576823 0.79 ALDH1A1 (0.36) AOC3LMNARIPK1FFAR1GPR84
SCHEMBL11811176 0.79 TSHR (0.37) AOC3FFAR1GPR84ALDH1A1
SCHEMBL2011658 0.79 CYP2C19 (0.37) AOC3LMNASLC6A4RIPK1HRH1
SCHEMBL2063541 0.77 ALDH1A1 (0.35) AOC3FFAR1GPR84ALDH1A1
SCHEMBL5033522 0.77 ALDH1A1 (0.35) AOC3LMNAFFAR1GPR84ALDH1A1
SCHEMBL4953718 0.77 ALDH1A1 (0.35) AOC3FFAR1GPR84ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922633-A The manufacture method of thermoplastic polymer composition 株式会社可乐丽 2018-04-17 CN disclosed
CN-107109052-A Thermoplastic resin composition and the formed body comprising it 三菱瓦斯化学株式会社 2017-08-29 CN disclosed
CN-104955893-A Thermoplastic polymer composition, shoes and outer soles KURARAY CO 2015-09-30 CN disclosed
CN-104684945-A Rheological agent, preparation methods and uses thereof OMNOVA SOLUTIONS 2015-06-03 CN disclosed