Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892508 | 0.86 | CA12 (0.66) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20116495 | 0.86 | CA12 (0.66) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16131376 | 0.83 | RAB9A (0.60) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13803643 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL892079 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14817520 | 0.80 | TSHR (0.76) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17321490 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19675708 | 0.80 | NPC1 (0.60) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20676025 | 0.79 | CA12 (0.74) | TSHRKMT2ACA12CA1CA2 | |
| SCHEMBL28309455 | 0.78 | SMN1; SMN2 (0.65) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |