Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676544 | 0.87 | ACACB (0.35) | MAPTLMNAACACBGAARAB9A | |
| SCHEMBL20116803 | 0.84 | MAPT (0.38) | MAPTLMNAACACBRAB9AMEN1 | |
| SCHEMBL20116872 | 0.81 | MAPT (0.40) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL20116844 | 0.81 | MAPT (0.35) | MAPTLMNAACACBRAB9AMEN1 | |
| SCHEMBL20116725 | 0.80 | MAPT (0.39) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL20117187 | 0.74 | MAPT (0.44) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL20116682 | 0.74 | NPC1 (0.53) | LMNAGAARAB9AMEN1KMT2A | |
| SCHEMBL20116718 | 0.73 | MAPT (0.40) | MAPTLMNAGAAPOLBTHRB | |
| SCHEMBL22358295 | 0.71 | PIK3CD (0.38) | MAPTLMNAACACBGAATHRB | |
| SCHEMBL20116766 | 0.71 | NPC1 (0.42) | GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |