Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116844 | 0.88 | MAPT (0.35) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL20676544 | 0.86 | ACACB (0.35) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL20116686 | 0.84 | MAPT (0.34) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL20117187 | 0.81 | MAPT (0.44) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL20116725 | 0.78 | MAPT (0.39) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL20116872 | 0.78 | MAPT (0.40) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL20116718 | 0.76 | MAPT (0.40) | MAPTLMNANPC1HTTTP53 | |
| SCHEMBL20116477 | 0.76 | MAPT (0.39) | MAPTLMNANPC1HTTMEN1 | |
| SCHEMBL20676705 | 0.73 | SMO (0.49) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL20117192 | 0.71 | TLR9 (0.51) | MAPTLMNAHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |