Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116883 | 0.91 | NPC1 (0.40) | SMOSMN1; SMN2HTTGAAKIT | |
| SCHEMBL20676703 | 0.80 | LMNA (0.39) | SMOSMN1; SMN2HTTGAAGRM5 | |
| SCHEMBL20116688 | 0.80 | CNR1 (0.39) | SMOSMN1; SMN2HTTGAAKIT | |
| SCHEMBL20116682 | 0.79 | NPC1 (0.53) | SMN1; SMN2HTTGAAGRM5KIT | |
| SCHEMBL20116798 | 0.79 | KIT (0.42) | SMOSMN1; SMN2HTTGAAKIT | |
| SCHEMBL20116847 | 0.79 | NPC1 (0.42) | SMOSMN1; SMN2HTTGAAKIT | |
| SCHEMBL20676542 | 0.77 | HTR4 (0.39) | SMOTLR9TLR8TLR7SMN1; SMN2 | |
| SCHEMBL20116766 | 0.77 | NPC1 (0.42) | SMN1; SMN2HTTGAAKITL3MBTL1 | |
| SCHEMBL20676506 | 0.76 | KIT (0.44) | SMOKIT | |
| SCHEMBL20676516 | 0.75 | SMN1; SMN2 (0.38) | SMOSMN1; SMN2HTTGAAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |