Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676424 | 0.79 | CYP3A4 (0.45) | USP2ALDH1A1HSD17B10CYP3A4CYP2C19 | |
| SCHEMBL20676431 | 0.79 | HSD17B10 (0.39) | USP2ALDH1A1HSD17B10CYP3A4CYP2C19 | |
| SCHEMBL20116435 | 0.72 | ALDH1A1 (0.41) | ARUSP2ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL15058808 | 0.65 | RXFP1 (0.62) | ALDH1A1HSD17B10CYP2C19HPGDCYP2C9 | |
| SCHEMBL1844242 | 0.63 | MAPT (0.73) | DCTPP1ALDH1A1CYP3A4CYP2C19MAPK1 | |
| SCHEMBL4171372 | 0.63 | KMT2A (0.73) | ALDH1A1HSD17B10CYP2C19HPGDCYP2C9 | |
| SCHEMBL25331880 | 0.63 | RXFP1 (0.59) | ALDH1A1HSD17B10CYP2C19HPGDCYP2C9 | |
| SCHEMBL10723816 | 0.63 | RAB9A (0.80) | ALDH1A1HSD17B10CYP2C19HPGDCYP2C9 | |
| SCHEMBL16000501 | 0.62 | TDP1 (0.64) | ALDH1A1CYP2C19CYP2C9KMT2AEPHX2 | |
| SCHEMBL3456393 | 0.62 | KMT2A (0.72) | ALDH1A1HSD17B10CYP2C19HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |