Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944094 | 0.98 | KMT2A (0.72) | KMT2ARXFP1RAB9AMEN1POLB | |
| SCHEMBL3454984 | 0.98 | KMT2A (0.72) | KMT2ARXFP1RAB9AMEN1POLB | |
| SCHEMBL3456393 | 0.98 | KMT2A (0.72) | KMT2ARXFP1RAB9AMEN1POLB | |
| SCHEMBL10723816 | 0.92 | RAB9A (0.80) | KMT2ARXFP1RAB9AMEN1POLB | |
| SCHEMBL10720608 | 0.86 | TSHR (0.69) | KMT2AMEN1POLBHPGDGLA | |
| (2-Chlorophenyl)(Morpholino)Methanone SCHEMBL6938284 | 0.84 | MGLL (0.68) | KMT2ARXFP1RAB9AGAAALDH1A1 | |
| SCHEMBL6673835 | 0.84 | RXFP1 (1.00) | KMT2ARXFP1RAB9AMEN1POLB | |
| SCHEMBL13503827 | 0.84 | KMT2A (0.88) | KMT2ARXFP1RAB9AMEN1POLB | |
| SCHEMBL29944015 | 0.84 | HPGD (0.67) | KMT2ARXFP1MEN1POLBHPGD | |
| SCHEMBL23793444 | 0.82 | HPGD (0.73) | KMT2ARXFP1RAB9AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | disclosed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | disclosed |
| US-4221805-A | N-(2-CHLOROBENZYL)PYRROLIDINE | QUADRO GIUSEPPE | 1980-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | NR3C1, NR3C2, MC2R | KMT2A 4088/4885RXFP1 826/4885RAB9A 3084/4885 |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | NR3C1, NR3C2, MC2R | KMT2A 4088/4885RXFP1 826/4885RAB9A 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.