Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978069 | 0.88 | THRA (0.56) | THRBPLK1ALDH1A1KDM4ECA2 | |
| SCHEMBL23736074 | 0.83 | RARB (0.62) | THRBPLK1ALDH1A1KDM4EGAA | |
| SCHEMBL14565742 | 0.82 | SMN1; SMN2 (0.61) | PLK1LPLLIPGALDH1A1CA2 | |
| SCHEMBL10957122 | 0.82 | THRB (0.57) | THRBPLK1L3MBTL1LPLLIPG | |
| SCHEMBL1363306 | 0.80 | THRB (0.55) | THRBPLK1L3MBTL1LPLLIPG | |
| SCHEMBL9098955 | 0.80 | THRB (0.55) | THRBPLK1L3MBTL1LPLLIPG | |
| SCHEMBL8420366 | 0.78 | PRSS1 (0.59) | THRBPLK1L3MBTL1 | |
| SCHEMBL10415435 | 0.78 | THRB (0.53) | THRBPLK1L3MBTL1LPLLIPG | |
| SCHEMBL7897931 | 0.78 | SMN1; SMN2 (0.69) | THRBPLK1L3MBTL1LPLLIPG | |
| SCHEMBL2464783 | 0.78 | PLK1 (0.60) | THRBPLK1L3MBTL1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160939-B1 | PROCESS FOR THE PRODUCTION OF A DIPEPTIDE DERIVATIVE | DSM IP ASSETS BV (NL) | 2018-05-02 | — | — | EP | disclosed |