Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.59 |
| ▸ | F10 | P00742 | 2/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10342835 | 0.98 | PRSS1 (0.57) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL8995527 | 0.88 | PRSS1 (0.55) | PRSS1PRSS2PRSS3F10LOXL2 | |
| Hydrochloric Acid SCHEMBL5884387 | 0.86 | PRSS1 (0.53) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL9649899 | 0.86 | ESR1 (0.55) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL9650566 | 0.84 | ESR1 (0.58) | THRBLMNA | |
| SCHEMBL9650583 | 0.84 | ESR1 (0.58) | THRBLMNA | |
| SCHEMBL9650690 | 0.84 | ESR1 (0.58) | THRBLMNA | |
| SCHEMBL9647294 | 0.84 | ESR1 (0.58) | THRBLMNA | |
| SCHEMBL9650482 | 0.84 | ESR1 (0.58) | THRBLMNA | |
| Hydrochloric Acid SCHEMBL7798271 | 0.84 | SPHK1 (0.56) | PRSS1PRSS2PRSS3F10LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109468659-A | The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase | 云南师范大学 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456273-A | The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase | 云南师范大学 | 2019-03-12 | — | — | CN | disclosed |
| US-9809621-B2 | Stable peptide-based PACE4 inhibitors | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2017-11-07 | — | — | US | disclosed |
| US-20170220717-A1 | FREE ENERGY CALCULATION DEVICE, METHOD, PROGRAM, AND RECORDING MEDIUM WITH THE PROGRAM RECORDED THEREON | TORAY INDUSTRIES, INC. (JP) | 2017-08-03 | — | — | US | disclosed |
| EP-1940856-B1 | NOVEL UROKINASE INHIBITORS | UNIV ANTWERPEN (BE) | 2014-10-08 | — | — | EP | disclosed |
| US-20140206622-A1 | STABLE PEPTIDE-BASED PACE4 INHIBITORS | SOCPRA Sciences Sante et Humaines S.E.C. (CA) | 2014-07-24 | — | — | US | disclosed |
| US-20120142718-A1 | N-17-Alkylated Prodrugs of Opioids | SIGNATURE THERAPEUTICS, INC. | 2012-06-07 | — | — | US | disclosed |
| US-8003627-B2 | Urokinase inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2011-08-23 | — | — | US | disclosed |
| US-8003627-B2 | Urokinase inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2011-08-23 | — | — | US | disclosed |
| US-20110177160-A1 | Amino acid lipids and uses thereof | MARINA BIOTECH, INC. (US) | 2011-07-21 | — | — | US | disclosed |
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | MARINA BIOTECH, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-20100112042-A1 | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics | MDRNA, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-7511039-B2 | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20080312191-A1 | Novel Urokinase Inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2008-12-18 | — | — | US | disclosed |
| US-20080312191-A1 | Novel Urokinase Inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2008-12-18 | — | — | US | disclosed |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INCORPORATED (US) | 2006-12-07 | — | — | US | disclosed |
| US-5112523-A | High clearing point for liquid crystal displays | CHISSO CORPORATION (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4874546-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1989-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130327-A1 | Multi-Arm Amines and Uses Thereof | SNRPE, SNRPA, ADAR | PRSS1 4466/4885PRSS2 4785/4885PRSS3 4740/4885 |
| US-20140206622-A1 | STABLE PEPTIDE-BASED PACE4 INHIBITORS | FURIN, DNPEP, PRAP1 | PRSS1 100/4885PRSS2 261/4885PRSS3 148/4885 |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | SERPINB1, SERPINE1, SERPINA2 | PRSS1 17/4885PRSS2 26/4885PRSS3 43/4885 |
| US-20100112042-A1 | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics | SLC27A2, LYPLA2, SLC47A2 | PRSS1 2168/4885PRSS2 982/4885PRSS3 3021/4885 |
| US-20080312191-A1 | Novel Urokinase Inhibitors | PLAU, PLAUR, SERPINE1 | PRSS1 65/4885PRSS2 114/4885PRSS3 124/4885 |
| US-20120142718-A1 | N-17-Alkylated Prodrugs of Opioids | OPRM1, OPRD1, OPRL1 | PRSS1 3321/4885PRSS2 3059/4885PRSS3 3486/4885 |
| US-20110177160-A1 | Amino acid lipids and uses thereof | AADAT, AARS1, ABAT | PRSS1 2415/4885PRSS2 2631/4885PRSS3 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.