Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | MASP2 | O00187 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 6/20 | 0.39 |
| ▸ | NPY4R | P50391 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117686 | 0.89 | F2 (0.52) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL8347873 | 0.82 | F2 (0.49) | MASP2F2MMP8 | |
| SCHEMBL18875317 | 0.81 | F2 (0.49) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL17366097 | 0.81 | F2 (0.49) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL20117449 | 0.80 | MASP2 (0.43) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL20117569 | 0.79 | MASP2 (0.43) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL20117448 | 0.79 | F2 (0.55) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL16938447 | 0.78 | MASP2 (0.42) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL20117568 | 0.77 | F2 (0.49) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL18878673 | 0.77 | F10 (0.50) | PSMB5NFKB1NFKB2RELAMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160939-B1 | PROCESS FOR THE PRODUCTION OF A DIPEPTIDE DERIVATIVE | DSM IP ASSETS BV (NL) | 2018-05-02 | — | — | EP | disclosed |