Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.49 |
| ▸ | MASP2 | O00187 | 2/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 7/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PROC | P04070 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117448 | 0.89 | F2 (0.55) | F2MASP2TMPRSS6F7NFKB1 | |
| SCHEMBL20117569 | 0.88 | MASP2 (0.43) | F2MASP2NFKB1PSMB5NFKB2 | |
| SCHEMBL20117686 | 0.87 | F2 (0.52) | F2MASP2TMPRSS6F7NFKB1 | |
| SCHEMBL17381408 | 0.83 | F2 (0.53) | F2MASP2TMPRSS6F10PLG | |
| SCHEMBL8347873 | 0.81 | F2 (0.49) | F2MASP2TMPRSS6F7ST14 | |
| SCHEMBL20117449 | 0.78 | MASP2 (0.43) | F2MASP2TMPRSS6NFKB1PSMB5 | |
| SCHEMBL20117685 | 0.77 | PSMB5 (0.42) | F2MASP2NFKB1PSMB5NFKB2 | |
| SCHEMBL8346207 | 0.77 | F2 (0.50) | F2MASP2TMPRSS6F7 | |
| SCHEMBL8354790 | 0.76 | F2 (0.49) | F2TMPRSS6F10PLGKLKB1 | |
| SCHEMBL8358318 | 0.74 | F2 (0.51) | F2TMPRSS6F10PLGKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160939-B1 | PROCESS FOR THE PRODUCTION OF A DIPEPTIDE DERIVATIVE | DSM IP ASSETS BV (NL) | 2018-05-02 | — | — | EP | disclosed |