SCHEMBL20118113

SCHEMBL20118113

CC(=O)OC(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
GALR3 O60755 1/20 0.37
MAPT P10636 1/20 0.37
BLM P54132 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALOX15 P16050 1/20 0.34
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
CYP2C19 P33261 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294879 0.78 LMNA (0.30) LMNA
SCHEMBL8965686 0.77 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL1502043 0.76
SCHEMBL2294883 0.76 ALDH1A1 (0.33) TSHRALDH1A1LMNA
Hydrochloric Acid SCHEMBL11629040 0.74 LMNA (0.32) TSHRALDH1A1LMNA
SCHEMBL7940239 0.74
SCHEMBL10657394 0.73 EPHX1 (0.32) TSHRALDH1A1TDP1CYP2C19
SCHEMBL5972068 0.73 LMNA (0.38) MAPTALDH1A1CYP2C19LMNA
SCHEMBL11592647 0.72 HCAR2 (0.38)
SCHEMBL11592654 0.72 HCAR2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3535363-B1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS PROCTER & GAMBLE (US) 2022-08-31 EP disclosed
EP-3535375-B1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS PROCTER & GAMBLE (US) 2022-08-31 EP disclosed
EP-3535364-B1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS PROCTER & GAMBLE (US) 2020-12-23 EP disclosed
EP-3535369-B1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS PROCTER & GAMBLE (US) 2020-09-09 EP disclosed
EP-3535372-B1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS PROCTER & GAMBLE (US) 2020-09-09 EP disclosed
US-10385294-B2 Leuco polymers as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2019-08-20 US disclosed
US-20180127590-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-10 US disclosed
US-20180119063-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed