Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 5/20 | 0.31 |
| ▸ | CNR2 | P34972 | 5/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118038 | 0.90 | CRHR1 (0.41) | CRHR1CRHR2HPGDMAPTNPSR1 | |
| SCHEMBL20118117 | 0.89 | KMT2A (0.41) | CRHR1CRHR2HPGDMAPTNPSR1 | |
| SCHEMBL20118068 | 0.87 | CRHR1 (0.39) | CRHR1CRHR2HPGDMAPTNPSR1 | |
| SCHEMBL20118128 | 0.85 | CRHR1 (0.38) | CRHR1CRHR2HPGDMAPTNPSR1 | |
| SCHEMBL20118225 | 0.85 | CRHR1 (0.38) | CRHR1CRHR2HPGDMAPTNPSR1 | |
| SCHEMBL20118152 | 0.84 | CRHR1 (0.36) | CRHR1CRHR2HPGDMAPTNPSR1 | |
| SCHEMBL18208281 | 0.84 | P2RX7 (0.35) | CRHR1CRHR2HPGDMAPTKMT2A | |
| SCHEMBL18208283 | 0.84 | P2RX7 (0.35) | CRHR1CRHR2HPGDMAPTKMT2A | |
| SCHEMBL18208365 | 0.84 | P2RX7 (0.35) | CRHR1CRHR2HPGDMAPTKMT2A | |
| SCHEMBL18216327 | 0.83 | P2RX7 (0.35) | CRHR1CRHR2HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |