Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118038 | 0.93 | CRHR1 (0.41) | CRHR1CRHR2ALDH1A1MAPTNPSR1 | |
| SCHEMBL20118225 | 0.92 | CRHR1 (0.38) | CRHR1CRHR2IP6K1ALDH1A1MAPT | |
| SCHEMBL20118128 | 0.92 | CRHR1 (0.38) | CRHR1CRHR2IP6K1ALDH1A1MAPT | |
| SCHEMBL20118117 | 0.92 | KMT2A (0.41) | CRHR1CRHR2ALDH1A1MAPTNPSR1 | |
| SCHEMBL20118055 | 0.91 | CRHR1 (0.36) | CRHR1CRHR2IP6K1ALDH1A1MAPT | |
| SCHEMBL20118196 | 0.87 | CRHR1 (0.36) | CRHR1CRHR2ALDH1A1MAPTNPSR1 | |
| SCHEMBL20118152 | 0.85 | CRHR1 (0.36) | CRHR1CRHR2ALDH1A1MAPTNPSR1 | |
| SCHEMBL18216524 | 0.84 | CRHR1 (0.39) | CRHR1CRHR2IP6K1ALDH1A1MAPT | |
| SCHEMBL18208204 | 0.81 | L3MBTL1 (0.40) | CRHR1CRHR2IP6K1ALDH1A1MAPT | |
| SCHEMBL20184989 | 0.81 | L3MBTL1 (0.40) | CRHR1CRHR2IP6K1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |